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KMID : 1103920120180030321
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Korean Journal of Hepatology
2012 Volume.18 No. 3 p.321 ~ p.325
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A case of necrotizing pancreatitis subsequent to transcatheter arterial chemoembolization in a patient with hepatocellular carcinoma
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Bae Song-I
Yeon Jong-Eun
Lee Jong-Mee
Kim Ji-Hoon
Lee Hyun-Jung
Lee Sun-Jae
Suh Sang-Jun
Yoon Eileen-L
Kim Hae-Rim
Byun Kwan-Soo
Seo Tae-Seok
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Abstract
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Necrotizing pancreatitis is one of the rare complications of transcatheter arterial chemoembolization (TACE). Necrotizing pancreatitis after TACE may result from the development of ischemia caused by regurgitation of embolic materials into the vessels supplying the pancreas. We report a case of post-TACE necrotizing pancreatitis with abscess formation in a patient with hepatocellular carcinoma. The patient had suffered hepatic artery injury due to repetitive TACE; during his 25th TACE procedure he had submitted to selective catheterization of the feeding vessel from the dorsal pancreatic artery with a cytotoxic agent and Gelfoam particles. The patient complained of abdominal pain after the TACE procedure, and a CT scan led to a diagnosis of necrotizing pancreatitis with abscess formation. The pancreatic abscess progressed despite general management of the pancreatitis, including antibiotics. Percutaneous catheter drainage was performed, and the symptoms of the patient improved.
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KEYWORD
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Carcinoma, Hepatocellular, Therapeutic chemoembolization, Acute necrotizing pancreatitis
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